99% Pure Lyophilized Powder in 3ml vial (NOT A LIQUID) – If Reconstitution is desired, please purchase our Reconstitution Solution, HERE
Want a shortcut to research?
Dispatched Within 24 Hours
Referenced in Human Studies
Third-Party COA Verified
Sourced from Trusted Labs in EU
Scientific Advisory Oversight
5-Amino-1MQ (5-amino-1-methylquinolinium) is a small molecule nicotinamide N-methyltransferase (NNMT) inhibitor developed to investigate metabolic regulation at the cellular level. NNMT is an enzyme expressed primarily in adipose tissue that plays a central role in energy metabolism and the regulation of NAD+ availability. By inhibiting NNMT, 5-Amino-1MQ research explores a novel pathway for influencing cellular energy balance without directly targeting hormone or receptor systems.
Store in a cool, dry place away from light.If Constituted, Please RefrigerateFor long-term storage, freezing at -20°C is recommended to maintain integrity.
Mechanism of Action
- Inhibits NNMT to reduce consumption of SAM (S-adenosylmethionine), a key methyl donor
- Supports intracellular NAD+ precursor availability, influencing sirtuin and PARP activity
- Modulates gene expression pathways associated with lipid metabolism and adipogenesis
Demonstrates selectivity for metabolically active tissue in preclinical models
Research Support
Research published in Nature Communications demonstrated that NNMT inhibition in adipose tissue reduced fat mass and prevented weight gain in diet-induced obese mouse models without observable systemic toxicity. Additional research has examined its role in preserving muscle stem cell function, with findings suggesting NNMT inhibition may support satellite cell activity relevant to skeletal muscle regeneration. Its dual relevance to metabolic and cellular aging pathways continues to make it a subject of active investigation.
For research purposes only. Not for human consumption or medical use.
Orders will typically be fulfilled to the following carriers within 24 hours of payment. USPS – (2 – 8 Business Days) UPS – (1 – 6 Business Days) *UPS HIGHLY RECOMMENDED*
Disclaimer: – This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.
Frequently Asked Questions
Our local team are here to help
Have more questions about peptide research? You’re not alone. Explore our Frequently Asked Questions for quick answers—or head to the Knowledge Base to explore study areas, calculators, and protocol guides.