99% Pure Lyophilized Powder in 3ml vial (NOT A LIQUID) – If Reconstitution is desired, please purchase our Reconstitution Solution, HERE
Want a shortcut to research?
Dispatched Within 24 Hours
Referenced in Human Studies
Third-Party COA Verified
Sourced from Trusted Labs in EU
Scientific Advisory Oversight
Semax is a heptapeptide analogue of the adrenocorticotropic hormone (ACTH) fragment 4–7, originally developed in Russia in the 1980s for research into cerebrovascular and cognitive function. Unlike its parent sequence, Semax does not produce adrenal effects, making it a cleaner research model for investigating neuroprotective and nootropic mechanisms independently of the HPA axis.
Mechanism of Action
- Upregulates brain-derived neurotrophic factor (BDNF) and its receptor TrkB, supporting neuronal survival and plasticity
- Modulates dopaminergic and serotonergic transmission in prefrontal and limbic regions
- Inhibits enkephalin-degrading enzymes, prolonging the activity of endogenous neuropeptides
- Demonstrates neuroprotective effects in ischemic and oxidative stress models
Store in a cool, dry place away from light.If Constituted, Please RefrigerateFor long-term storage, freezing at -20°C is recommended to maintain integrity.
Research Support
Research published in the Journal of Molecular Neuroscience documented significant BDNF upregulation following Semax administration in rodent models, with associated improvements in memory consolidation tasks. Separate studies have examined its utility in stroke recovery models, where Semax-treated subjects demonstrated reduced lesion volume and faster restoration of neurological function compared to controls. Its resistance to rapid enzymatic degradation relative to native ACTH fragments has made it a preferred research compound for sustained CNS investigation.
For research purposes only. Not for human consumption or medical use.
Orders will typically be fulfilled to the following carriers within 24 hours of payment. USPS – (2 – 8 Business Days) UPS – (1 – 6 Business Days) *UPS HIGHLY RECOMMENDED*
Disclaimer: – This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.
Frequently Asked Questions
Our local team are here to help
Have more questions about peptide research? You’re not alone. Explore our Frequently Asked Questions for quick answers—or head to the Knowledge Base to explore study areas, calculators, and protocol guides.