Why Peptides Arrive Lyophilized


Peptides are highly sensitive molecules. To ensure stability during shipping and long-term storage, they are typically supplied in a lyophilized (freeze-dried) form. Removing water protects peptide integrity, slows degradation, and makes storage more reliable.

Before use in research, peptides must be reconstituted — restored to a solution state using a suitable medium. This step is fundamental because dry peptides cannot participate in experimental systems until they are dissolved.

Conceptual Overview of Reconstitution


While every peptide is unique, researchers generally consider the
following conceptual checkpoints before reconstitution:

  • Review documentation: Vendor datasheets and Certificates of Analysis (COAs) contain essential information on purity and handling.
  • Define research purpose: Concentration and medium choice depend on experimental design.
  • Assess stability factors: Some peptides are more prone to degradation once in solution.
  • Plan for storage and aliquots: Consider whether the peptide will be used immediately or stored in working stocks.
  • Seek oversight: Final decisions should align with institutional SOPs and supervisor approval.

⚠️ Note: This overview is educational only. It is not an operational guide or protocol.

Reconstitution Calculator


To support researchers in planning, Lumin provides a Reconstitution Calculator. This tool helps you explore theoretical concentration and volume relationships when preparing solutions.

Use the Reconstitution Calculator

Disclaimer: The calculator is for conceptual planning only. It does not replace vendor datasheets, institutional SOPs, or supervisor instructions.